Peroxisome prolifreator-activated receptors and neurodegenerative diseases / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
en Zh
| WPRIM
| ID: wpr-558671
Biblioteca responsable:
WPRO
ABSTRACT
Peroxisome prolifreator-activated receptors (PPARs) are ligand-activated nuclear transcription factors, members of nuclear hormone receptor superfamily. PPARs play critical roles in growth, proliferation and apoptosis of variety of cells. Recently, PPAR ligands have been reported to ameliorate neuronal damage in neurodegenerative diseases including Alzheim- ers disease, Parkinsons disease,cerebral ischemia and multiple sclerosis. PPAR agonists may have potential values in treatment of neurodegenerative diseases. In this paper, we reviewed recent findings on PPARs′ neuroprotective actions and their underlying mechanisms.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
1986
Tipo del documento:
Article