Study on Moulding Technics of Anxinkang Drop Pills / 浙江中医药大学学报

ABSTRACT

[Objective]To study the optimum techniques making Anxinkang drop pills. [ Methods ] Using parallel experimentation for the choice of Matrix and refrigerant,dropping distance and rate,the temperranture of refrigerant.Using orthogonal experimentation for the choice of proportion of extract and Matrix,proportion of extract,water and glycerin, the temperature of drug solution.with quality of outward appearance as the evalution quota to decide the best dropping condition.[ Results ]The optimum technique was that PEG6000∶PEG4000(3∶2) as matrix,Methyl-siliconoilliquid-paraffin(3∶1) is refigerant.Internal and external diameter of burette are equal to 2.5mm and 3mm .Drug is dropping into the refrigerant of about15~20 drop per minute [ conclusion ] The oplimum techniques are feasible and accord with the quality standards of drop pills.