Effect of L-arginine supplemented enteral nutrition on cellular immunological function in rats with severe head injury / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6)2004.
Artículo
en Chino
| WPRIM
| ID: wpr-559181
ABSTRACT
Objectives:
The study was designed to observe the effects of L-arginine(Arg) supplemented enteral nutrition on cellular immunological function in rats with severe head injury.Method:
The severe head injury of rats was produced by gas percussion.Thirty rats were divided randomly into 3 groups(n=10) normal control group,enteral nutrition(EN)group and EN+Arg group.Rats in groups EN and EN+Arg were supplemented with tyrosine at the does of 0.8g?kg~(-1)?d~(–1)and Arg at the dose of 0.8g?kg~(-1)?d~(–1)for 7days,respectively.Blood samples were collected after 7 days.PMN phagocytosis rate was observed by phagocytosis Candida albicans count.CD4~(+)cells and CD8~(+) cells were analyzed by SABC.The concentration of serum IL-2 level was measured by radioimmunoassay.Results:
Decreased cellular immunolgical function was found on 7~(th) day after severe head injury.However,CD4~(+),CD4~(+)/CD8~(+),IL-2 level and PMN phagocytosis rate in EN +Arg group were better than that in EN group.There was significant difference in each immunological index(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Parenteral & Enteral Nutrition
Año:
2004
Tipo del documento:
Artículo
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