Effectiveness of drug eluting stents in patients with small coronary artery lesions / 中国实用内科杂志

ABSTRACT

Objective To assess the safety and effectiveness of the drug eluting stents(DES,including Cypher and TAXUS stent)in treating patients with single- and multi-vessel de novo lesions located in small native coronary arteries with comparison of bare metal stent(BMS).Methods From December 2002 to May 2005,coronary stenting procedures were performed in 407 patients with small coronary artery lesions consecutively(among whom 150 patients with multi-vessel small coronary lesion).There were 214 patients(63 patients with multi-vessel)in BMS group,140 patients(46 patients with multi-vessel)in Cypher group and 132 patients(41 patients with multi-vessel)in TAXUS group.The results of in-hospital and 6-month clinical follow-up were analysed among the 3 groups.Results There were no differences in lesion characteristic,success rate of percutanous coronary intervention(PCI),in-hospital major adverse cardiac events(MACE)and in-stent minimal lumen diameter after PCI among 3 groups.However,angiographic restenosis occurred significantly less in two DES groups than in BMS group(4.9%in Cypher group and 7.5%in TAXUS group vs 29.2% in BMS group,P