The effect and mechanism of genistein on collagen synthesis of growth plate chondrocytes / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-559727
ABSTRACT
Aim To investigate effects of genistein (5, 7, 4′-trihydroxyisoflavone) on rat costochondral growth plate chondrocyte (RGC) collagen and Sox9 expression. Methods Primary cultured RGC, effects of genistein on collagen synthesis, col2a1 mRNA transcription and Sox9 protein expression of 1st passage RGC were detected by isotope incorporation, RT-PCR and western blotting. Results Genistein inhibited collagen synthesis of 1st passage RGC (P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Pharmacological Bulletin
Año:
2003
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS