The Effect of Fentanyl and Remifentanil on Postoperative Nausea and Vomiting, and Pain after Gynecologic Laparoscopic Ovarian Cyst Enucleation by Balanced Anesthesia with Sevoflurane / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 390-395, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-56159
ABSTRACT
BACKGROUND:
Opioids are known to increase the incidence of postoperative nausea and vomiting (PONV). Remifentanil is an ultrashort-acting opioid with a potent analgesic effect and is useful for rapid emergence. This study compared the effect of remifentanil on the incidence and severity of PONV and postoperative pain with that of fentanyl in patients undergoing laparoscopic surgery, which is normally associated with a high incidence of PONV.METHODS:
Forty-four adult female patients, who were scheduled for laparoscopic ovarian cyst enucleation, were randomly assigned to either the remifentanil or fentanyl group. Anesthesia was induced with propofol after injecting fentanyl 2 microgram/kg or remifentnail 1 microgram/kg and was maintained with sevoflurane. Remifentanil and fentanyl was infused continuously in the range of 0.2-0.5 microgram/kg/min and 0.03-0.05 microgram/kg/min, respectively. Ketorolac 0.5 mg/kg was injected 30 min before the end of surgery. The incidence and severity of PONV and pain were recorded upon arrival at the recovery room and 2, 6, 12 and 24 hours thereafter.RESULTS:
The incidence and severity of PONV and pain were significantly higher in the remifentanil group upon arrival at the recovery room than in the fentanyl group. The incidence and severity of PONV and pain at the other measurement times were similar.CONCLUSIONS:
Despite the ultrashort action duration of the remifentanil, the incidence and severity of PONV and postoperative pain immediately after awakening was higher in the remifentanil group undergoing laparoscopic ovarian cyst enucleation than in the fentanyl group. However, there were no significant differences after two hours in the recovery phase.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Quistes Ováricos
/
Dolor Postoperatorio
/
Sala de Recuperación
/
Propofol
/
Fentanilo
/
Incidencia
/
Laparoscopía
/
Náusea y Vómito Posoperatorios
/
Ketorolaco
/
Anestesia Balanceada
Tipo de estudio:
Estudio de incidencia
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Anesthesiology
Año:
2006
Tipo del documento:
Artículo
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