THE DISTRIBUTION OF HFE GENE MUTATION IN CHINESE ADULT MEN / 营养学报
Acta Nutrimenta Sinica
;
(6)1956.
Artículo
en Chino
| WPRIM
| ID: wpr-561959
ABSTRACT
Objective:
To analyze the distribution of HFE gene (hemochromatosis gene) mutation in normal and iron overload men and discuss the influence of HFE gene mutation on iron overload status of Chinese adult men..Method:
The data of 226 normal and 331 iron overload men were drawn from National Nutrition and Health Survey in 2002 as control and case group respectively to analyze and compare the distribution of HFE mutation including C282Y mutation, H63D mutation and S65C mutation in normal and iron overload men.Results:
In case group, normal gene was 90.03%, homozygosity for H63D mutation 0.6%, heterozygosity for H63D mutation 9.07%, heterozygosity for S65C 0.3%. In control group normal gene was 94.25%, heterozygosity for H63D 5.75%, and no S65C and C282Y mutation was detected.Conclusion:
HFE gene mutation was not the major reason resulting in iron overload in Chinese adult men.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Acta Nutrimenta Sinica
Año:
1956
Tipo del documento:
Artículo
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