STUDY ON EFFECTS AND MECHANISM OF SOYBEAN ISOFLAVONES ON UTERI IN PERIMENOPAUSAL RATS / 营养学报
Acta Nutrimenta Sinica
;
(6)2004.
Artículo
en Chino
| WPRIM
| ID: wpr-562628
ABSTRACT
Objective:
To observe the effects of soybean isoflavones(SI) on uteri and uterine Er?,ER? expression in perimenopausal rats.Method:
Female SD rats in age of 7-month-old were used as control and 11-month-old SD rats were divided into 5 groups,model group,diethylstilbestrol group and 3 test groups exposed to three doses of SI(ig30,12,4.6 mg/kg?d) respectively for 35 d. Serum concentrations of estradiol(E2) ,testosterone(T) ,follicle-stimulating hormone(FSH) and luteinizing hormone(LH) were determined. Ultrastructure of uterine luminal surface was observed by scanning electron microscopy and hematoxylin-eosin staining. Expression of ER? and ER? in the uteri were determined by immunohistochemistry.Results:
Low dose SI significantly increased serum E2(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Acta Nutrimenta Sinica
Año:
2004
Tipo del documento:
Artículo
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