Application of proteomics in the study of molecular mechanism of morphine dependence / 中国药理学通报

ABSTRACT

Proteomics has been applied in a wide range of biomedical research.However,the application of proteomics in studying the molecular mechanism of morphine dependence is only at a preliminary stage.This article introduced the application of proteomics techniques in the study of the molecular mechanism of morphine dependence and the discovery of several potential molecular markers of morphine dependence,which affirmed the importance and potential of proteomics in this research area.Also,it was pointed out that the major tasks of current proteomic study of morphine dependence should include establishing animal and cell models of morphine dependence,selecting appropriate sample source and improving proteomics techniques,so that proteomics can serve as a new approach in the study of morphine dependence to discover new therapeutic targets.