Safety evaluation of endovascular stent implantation in treating carotid artery stenosis / 中国组织工程研究

ABSTRACT

OBJECTIVE:To evaluate the safety of endovascular stent implantation in treating carotid artery stenosis and analyze the stenosis rate and hemodynamics following stent implantation.METHODS:Self-control experiments concerning endovascular stent implantation for carotid artery stenosis were searched in CNKI published between 2000 and 2008 with the of "carotid artery stenosis,endovascular stent implantation".The data of each experiment were extracted and analyzed.RESULTS:A total of 17 experiments involving 522 cases of carotid artery stenosis were accorded with the inclusion criteria.The stenosis rate was reduced after endovascular stent implantation.Follow-up results show that the stent has good appearance with no deformation,and the blood flow is patent in the stent,with no relapse of re-stenosis.In addition,stent implantation promotes recovery of blood flow at stenosis site,improves distal blood flow rate,attenuates blood perfusion and hemodynamic impairment and reduce stroke incidence.CONCLUSION:Endovascular stent implantation has high success rate in treating carotid artery stenosis with favorable clinical outcome.However,other effective indexes and its safety need further evaluation.