Effect of Ruhuang preparation on endotoxin and intestinal defence function of cirrhotic rats / 中华中医药杂志

ABSTRACT

Objective: To study the influence of Ruhuang(Rhubarb and Lactohacillin) preparation to endotoxin and intestinal defence function of cirrhotic rats.Methods:88 male Wister rats were randomly divided into normal group,model group,prevention group,prevention of control group,model treatment group and model treatment of control group.Liver cirrhosis model was induced by CCl4 combined with other factors,Ruhuang preparation was used for the prevention and treatment,lactulose was used as positive control drug.The level of plasma endotoxin,intestinal mucosal S-IgA and serum D-lactic acid were detected.Results: The blood plasma endotoxin level of Ruhuang prevention group and model treatment group is lower than that of model group obviously(P