Influence of Breviscapine Injection on IGF of Pregnant Rats and Growth of Fetus Rats / 国际中医中药杂志

ABSTRACT

Objective To discuss the influence of Breviscapine Injection on concentration of serum IGF-Ⅱ in pregnant rats and changes of fetus rat body weight, body length, and body-mass index. Methods Radio-immunity was used to determine the concentration of serum IGF- Ⅱ in mother rats and fetus rats. Body weight and body length were surveyed,the IGF- Ⅱ concentration of fetus rats in the FGR group was lower than the control group (P＜0.05) and IGF- Ⅱ concentration control group＞the FGR+intervention group＞ the FGR group, and the difference between each group was significant (P＜0.05).Breviscapine can treat fetal growth retardation effectively.