Silent Colonic Malakoplakia in a Living-Donor Kidney Transplant Recipient Diagnosed during Annual Medical Examination
Korean Journal of Pathology
; : 163-166, 2013.
Article
en En
| WPRIM
| ID: wpr-56546
Biblioteca responsable:
WPRO
ABSTRACT
Malakoplakia is a characteristic inflammatory condition, which is usually seen in the urogenital tract, and less frequently in the gastrointestinal tract. We present a case of colonic malakoplakia in an immunocompromised patient. A 55-year-old female visited the outpatient clinic for routine cancer surveillance. Her past medical history was significant for kidney transplantation 11 years ago, and she had been taking immunosuppressants. A colonoscopy revealed several depressed flat lesions and elevated polyps, which were 0.3 to 0.4 cm in size and accompanied by whitish exudates. A biopsy revealed an infiltration of histiocytes with ample granular eosinophilic cytoplasm, with some lymphocytes and plasma cells. Many histiocytes had the characteristic morphology, described as Michaelis-Gutmann bodies: one or several round basophilic structures of approximately 1 to 10 microm in size with some being laminated, some appearing homogeneous, and others having a dense central core with a targetoid appearance. These Michaelis-Gutmann bodies were positively stained on von Kossa stain, and were diagnostic for malakoplakia.
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Texto completo:
1
Índice:
WPRIM
Asunto principal:
Células Plasmáticas
/
Pólipos
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Basófilos
/
Biopsia
/
Linfocitos
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Colonoscopía
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Trasplante de Riñón
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Huésped Inmunocomprometido
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Colon
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Trasplantes
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Korean Journal of Pathology
Año:
2013
Tipo del documento:
Article