STUDY OF INHIBITIVE EFFECT OF KONJAC POLYSACCHARIDE ON INTESTINAL ABSORPTION FUNCTION OF MICE AND ITS MECHANISM / 营养学报

ABSTRACT

Objective To investigate the inhibitive effect of Konjac polysaccharide(KP) on intestinal absorption function of mice and its mechanism.Method Mice were divided into normal control(N),high fat(HF),and high,middle,low dose KP(KPH,KPM,KPL) treated groups.Intestinal mucosa Na+-K+-ATPase activity was determined by UV spectrophotometry,blood glucose was determined by fast meter after twenty days.Body weight,fecal wet weight and dry weight were also examined.Results Na+-K+-ATPase activity of HF and KPH groups were 16.2?1.48 and 11.2?1.10 ?mol Pi/(mg prot?h),respectively.Body weight and postprandial blood glucose were 34.3?2.07 g,7.5?1.15 mmol/L and 28.1?1.95g,4.8?0.73 mmol/L,respectively.The differences between two groups were significant(P