Establishment of the diarrhea-predominant IBS SD rat model and appraisal of its sensitivity / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)1986.
Artículo
en Chino
| WPRIM
| ID: wpr-565634
ABSTRACT
Aim To establish diarrhea-predominant IBS SD rat model and appraise its intestinal tract.Method The postnatal rat of 8~21 days were given the successive stimulation of the inflammation inside the colon(rectum abouchement 0.087 mol?L-1 acetic acid 0.5 ml)to replicate the animal model of the IBS visceral hypersensitive.The change of IBS SD rat model organ sensitivity was studied,and the change of threshold of pain at ectocolon of model rat was observed,as well as the influence of excised intestinal canal systaltic motion with convulsion-induced agent for model rat.Results Model group was obviously lower than normal group with pressure threshold value of raise abdomen and extrados in the eighth week and the sixth week(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Chinese Pharmacological Bulletin
Año:
1986
Tipo del documento:
Artículo
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