A Case of Foreign Body Granuloma Caused by Subcutaneous Injection of Leuprorelin Acetate / 대한피부과학회지
Korean Journal of Dermatology
;
: 634-637, 2016.
Artículo
en Coreano
| WPRIM
| ID: wpr-56622
ABSTRACT
Leuprorelin acetate is a synthetic analog of luteinizing hormone-releasing hormone (LHRH). Recently, hormone-dependent tumors (prostate cancer and breast cancer) have been treated without surgery using this LHRH agonist. A 74-year-old man presented with a subcutaneous tumor in the abdomen. He had received a subcutaneous injection of depot leuprorelin acetate 2 months previously and radiotherapy for prostate cancer. The subcutaneous tumor was totally excised. Histopathologic findings revealed necrosis of fat tissue, many granulomatous nodules composed of giant cells with vacuoles in the dermis and subcutis, and inflammatory cell infiltrates, including mainly lymphohistiocytes. A diagnosis of foreign body granuloma due to depot injection of leuprorelin acetate was made. He revisited our hospital after 1 month with a subcutaneous tumor on his Lt. upper arm. He had received a subcutaneous injection of leuprorelin acetate 1 week ago on that site. We treated it with intralesional triamcinolone injection. Here, we report a case of granulomatous reaction due to leuprorelin acetate injection, which produced subcutaneous nodules.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Brazo
/
Neoplasias de la Próstata
/
Radioterapia
/
Vacuolas
/
Mama
/
Triamcinolona
/
Células Gigantes
/
Granuloma de Cuerpo Extraño
/
Hormona Liberadora de Gonadotropina
/
Leuprolida
Tipo de estudio:
Estudio diagnóstico
Límite:
Anciano
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS