Research development and clinical significance of genetic polymorphism of CYP450 / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12)2004.
Artículo
en Chino
| WPRIM
| ID: wpr-566506
ABSTRACT
Cytochrome P450 is the very most important enzyme of drug metabolism.It involves in biotransformation of various endogenous and exogenous compounds,especially for clinical drugs.There are many polymorphisms of gene and phenotype,resulting in significant individual variability of different kinds of compounds.This article reviews the genetic polymorphisms of CYP,the characters and clinical meanings of diverse subgroups that relevant to drug metabolism in recent years.The major object of this article is reasonably explaining and predicting the interaction of clinical drugs and the drug adverse reaction in order to providing scientific evidences for the individual administration in clinic.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Clinical Pharmacology and Therapeutics
Año:
2004
Tipo del documento:
Artículo
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