Downregulation of P2X_7 receptor expression in neonatal rats after hypoxic-ischemic brain damage / 第三军医大学学报
Journal of Third Military Medical University
;
(24)2003.
Artículo
en Chino
| WPRIM
| ID: wpr-566663
ABSTRACT
Objective To investigate the change of P2X7 receptor expression in neonatal rats after hypoxic-ischemic brain damage(HIBD).Methods Twenty SD rats were randomized into 2 groups,control group and hypoxic-ischemic(HI) group.Western blotting and immunohistochemistry was used to detect the protein expression of P2X7 receptor in cerebal cortex,subcortical white matter and hippocampus before and after hypoxia-ischemia.Results In comparison to the sham operation controls,a significant down-regulation of the P2X7 receptor protein was observed in ischemic cerebral cortex,subcortical white matter(P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Chino
Revista:
Journal of Third Military Medical University
Año:
2003
Tipo del documento:
Artículo
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