Micafungin in the management of invasive fungal infections / 中国实用内科杂志

ABSTRACT

Micafungin is a novel echinocandin antifungal agent,with a special michanism of action and broad spectrum fungicida activity against both Candida spp.and Aspergillus spp.It has been shown to be safe and effective for the treatment of invasive fungal infections(IFIs)in some clinical setting or trials.In recent years,it is playing an increasingly important role in the field of antifungal.Therefore,we analyzed and reviewed the antifungal efficacy,pharmacoeconomics,application in the special populations and drug interactions of micafungin based on the pharmacology & pharmacodynamics of micafungin and cited several correlated clinical trial in this article.