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Development and application of models for screening torsade de pointes induced by drugs / 中国药理学通报
Chinese Pharmacological Bulletin ; (12)2003.
Artículo en Chino | WPRIM | ID: wpr-567977
ABSTRACT
In recent years,a large number of drugs have been withdrawn from the market because of torsade de pointes(TdP) and sudden cardiac death,which pose great risks in drug application.Therefore,the different models have been developed to detect TdP liability during the early stage of drug development.In this paper,the principles and characteristics of these screening models are reviewed to give props for preclinical safety assessment.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio diagnóstico / Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: Chinese Pharmacological Bulletin Año: 2003 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio diagnóstico / Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: Chinese Pharmacological Bulletin Año: 2003 Tipo del documento: Artículo