Survivin variants' expression in gastric cancer cells and its relationshiop with proliferation and apoptosis / 中华消化杂志
Chinese Journal of Digestion
;
(12)2001.
Artículo
en Chino
| WPRIM
| ID: wpr-572544
ABSTRACT
Objective To study the expression of three survivin splicing variants in gastric cancer and normal gastric mucosa and to evaluate relationship among the survivin variants' expression and proliferation, apoptosis in gastric cancer. Methods Real time quantitative RT-PCR was used to analyze survivin variants expression in 77 paired tumors and normal gastric mucosa in frozen samples at the mRNA level. The cell proliferation and apoptosis were measured by Ki-67 immunoln's to chemical analysis and TUNEL method in paraffin-embedded block of same cases, respectively. Results The sarvivin splicing variants were remarkably up-regulated in gastic cancers compared with those in normal tissues (P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Digestion
Año:
2001
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS