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Survivin variants' expression in gastric cancer cells and its relationshiop with proliferation and apoptosis / 中华消化杂志
Chinese Journal of Digestion ; (12)2001.
Artículo en Chino | WPRIM | ID: wpr-572544
ABSTRACT
Objective To study the expression of three survivin splicing variants in gastric cancer and normal gastric mucosa and to evaluate relationship among the survivin variants' expression and proliferation, apoptosis in gastric cancer. Methods Real time quantitative RT-PCR was used to analyze survivin variants expression in 77 paired tumors and normal gastric mucosa in frozen samples at the mRNA level. The cell proliferation and apoptosis were measured by Ki-67 immunoln's to chemical analysis and TUNEL method in paraffin-embedded block of same cases, respectively. Results The sarvivin splicing variants were remarkably up-regulated in gastic cancers compared with those in normal tissues (P

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Digestion Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Digestion Año: 2001 Tipo del documento: Artículo