Determination of protocatechuic acid and protocatechualdehyde in Compound Sijiqing Tablets by HPLC / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Artículo
en Chino
| WPRIM
| ID: wpr-572616
ABSTRACT
AIM:
To establish an external standard HPLC method for the determination of protocatechuic acid and protocatechualdehyde in Compound Shijiqing Tablets(Folium Ilicis Chinensis, etc.).METHODS:
Alltima C 18(5?m, 4.6mm?250mm)was used. The mobile phase was consisted of methanol-1% acetate(18∶82). The flow rate was 1.0mL?min -1. The UV detection wavelength was at 280nm.RESULTS:
The two components has good resolution. The liner ranges were in the range of 7.6~127.1?g?mL -1 for protocatechuic acid and in the range of 2.62~43.6?g?mL -1 for protocatechualdehyde with the correlation coefficients 0.9997 and 0.9994, respectively. The average recoveries were 99.9% and 97.5% with RSD 2.1%,2.2%(n=5), respectivelyCONCLUSION:
The method is accurative, reproducible and can be used to control the quality of Compound Sijiqing Tablets.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Traditional Patent Medicine
Año:
1992
Tipo del documento:
Artículo
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