Clinical analysis on 78 cases of typhoid fever and paratyphoid fever / 重庆医科大学学报

ABSTRACT

Objective:To investigate the clinical features of typhoid fever and paratyphoid fever in Chongqing.Methods:A retrospective study was designed to analyze 78 cases of typhoid fever and paratyphoid fever from 1999 to 2003.Results:The proportion of typhoid fever was decreased,but the proportion of paratyphoid fever rose from 20% in 1999 to 55.6% in 2003.The clinical manifestations included fever,relative bradycardia,hepatosplenomegaly,leukopenia and diarrhea,infrequently as roseola and indifferent expressions.The complications mostly manifested as toxic hepatitis and bronchopneumonia.Typhoid fever and paratyphoid fever were sensitive to fluoro -quinolones and the third generation cephalothins.Conclusion:In recent years proportion of paratyphoid fever tend to rise.Fluoro-quinolones still remain the drug of choice for the treatment of typhoid and paratyphoid fever.