Changed DBH expression of the neurons in lumbar sympathetic ganglia in response to Buerger's disease of lower limb / 重庆医科大学学报

ABSTRACT

Objective:To observe the expression of dopamme beta hydroxylase (DBH) in the lumbar sympathetic ganglia neurons of the patients with Buerger's disease of lower limb.Methods:The DBH expression of the neurons in lumbar sympathetic ganglia of 14 patients with Buerger's disease were observed by immunohistochemistry staining.11 patients without it served as the controls.Results:The DBH expression of the patients were reinforced that of control group.Conclusion:The enhanced expression of DBH may result in vasospasm,accelerating the development of Buerger's disease.