Preventive Effect of Compound Zaofan Pills on Bone Marrow Arrest in Patients with Non-small-cell Lung Cancer After Chemotherapy / 广州中医药大学学报

ABSTRACT

[ Objective ] To observe the protective effect of Compound Zaofan Pills ( CZP) , a prescription mainly composed of Radix Panacis Quinquefolii, Hippocampus Histrix, Melanteritum, Fructus Jujubae, Semen Juglandis, Cortex Cinnamomi, etc. , on bone marrow in patients with non-small-cell lung cancer ( NSCLC) after plantinum chemotherapy. [Methods] Sixty-five cases of intermediate and late NSCLC were randomized into two groups. Group A was treated with CZP and chemotherapy and group B with chemotherapy alone. After treatment, ranking of bone marrow arrest and time for leukocytes recovering to normal were observed in the two groups. [ Results ] After 2 treatment courses, chemotherapy-done percentage was 91.6% (33/36) in group A, higher than 68.9% (20/29) in group B (P