What Is an Optimal Dose of Sufentanil for Attenuating the Hemodynamic Response to Tracheal Intubation?
Anesthesia and Pain Medicine
;
: 78-82, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-57355
ABSTRACT
BACKGROUND:
Laryngoscopy and tracheal intubation often cause hemodynamic changes such as hypertension and tachycardia. This study was carried out to determine the optimal dose of sufentanil for attenuating the hemodynamic changes that occur during the induction of anesthesia with propofol.METHODS:
The authors examined 100 ASA class 1-2 patients, who were scheduled for elective surgery anddivided randomly into 4 groups. Anesthesia was induced with propofol (5.0microg/kg target controlled infusion). Three minutes later, rocuronium 1.2 mg/kg was administered. Group 1 (CON group) received no sufentanil, and groups 2, 3 and 4 (SO3, SO5, SO7 groups) received 0.3, 0.5, 0.7 microg/kg, sufentanil, respectively. The hemodynamic changes and BIS were measured at preinduction, 1 and 3 minutes after propofol infusion, and 1 and 3 minutes after sufentanil infusion, intubation, and post-intubation period for 10 minutes.RESULTS:
In the SO3, SO5, SO7 groups, the systolic and diastolic and mean arterial pressure did notincrease compared with that at preinduction. However, in the SO7 group, the systolic and diastolic and mean arterial pressure decreased significantly 1 minute after intubation. In the SO3 group, the heart rate increased significantly after intubation compared with preinduction. On the other hand, the heart rate did not increase after intubation in the SO5 and SO7 groups.CONCLUSIONS:
When anesthesia is induced with propofol TCI (5.0 microg/ml, the authors suggest that the recommended dosage of sufentanil for attenuating the hemodynamic changes accompanying a laryngoscopy and tracheal intubation be approximately 0.5microg/kg.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Taquicardia
/
Propofol
/
Sufentanilo
/
Presión Arterial
/
Mano
/
Frecuencia Cardíaca
/
Hemodinámica
/
Hipertensión
/
Intubación
/
Intubación Intratraqueal
Límite:
Humanos
Idioma:
Coreano
Revista:
Anesthesia and Pain Medicine
Año:
2006
Tipo del documento:
Artículo
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