The study of event related potential P_(300) in patients with anxiety disorder / 中华物理医学与康复杂志

ABSTRACT

Objective To investigate the characteristics of event related potential(ERP) P 300 in patients with anxiety disorder. Methods Thirty patients with anxiety disorder (AD group), diagnosed with CCMD 2R, and 30 normal people (NC group) were recruited. The odd ball auditory evoked model was used to test ERP P 300. Results All waveforms of P 300 were clear. (1)Target stimuli At Fz、Cz electrodes position, compared with those in NC group[respectively (263.3?18.9)ms and(259.5?13.8)ms], latencies of target N2 in AD group were significantly longer [respectively (282.7?34.6)ms and(277.9?22.6)ms](P0.05). (2)Non-target stimuli At Fz electrodes position, the amplitudes of non-target P2 in AD group[(2.3?1.3)?V] were lower than that in NC group[(3.4?1.0)?V] (P