Evaluation of long-term efficacy of supplementary Lei's Danshen Tablet therapy in ischemic cardiomyopathy patients with heart failure / 中成药

ABSTRACT

AIM: To evaluate the long-term clinical efficacy of supplementary Danshen Tablet therapy in ischemic cardiomyopathy patients with heart failure. METHODS: 100 ischemic cardiomyopathy patients with heart fai-lure were randomly assigned into two groups,Danshen group(50 patients) and conventional therapy group(50 patients).The patients in Danshen group were administrated Danshen Tablet(three tablets a time,three times a day) plus conventional therapy for one year.NYHA functional class,6 min walking-distance,echocardiographic indices,major-adverse-cardiovascular-events(MACE) and mortality were evaluated before and after 1 year therapy.(RESULTS)(After) 1 year therapy,the improvements of NYHA functional class and 6 min walking-distance were more significantly effective in Danshen group than those in conventional group(P