Determination of Ferulic Acid in Fuke Shiwei Jiaonang Capsule by HPLC / 中国中医药信息杂志

ABSTRACT

Objective To develop the method for determining the concert of Ferulic acid. Method The Ferulic acid in Fuke Shiwei Jiaonang capsule was determinined by HPLC. The analytical column was Hanbon Lichrospher (250 mm?4.6 mm?5 ?m) and mobile phase was Acetonitrile-0.085% phosphate acid(17∶83). Ferulic acid was detected at 230 nm. Results In the scope of 0.0204～0.102 ?g, the contents of Ferulic acid had good liner relationship with their peak area (r =0.9999, n =5). The average recovery rate was 98.32%, RSD was 1.64% (n =5). Conclusion The method was rapid, simple and precise.