Effect of Fuxin Tablet on Thrombus Formation in the Arteries in Rats and Aggregation of the Blood Platelet in Rabbits / 中国中医药信息杂志

ABSTRACT

Objective To investigate the effect of Fuxin tablet on thrombus formation in the arteries in rats and aggregation of platelet in rabbits. Methods To observe the effect of OT in the arteries through electric stimulation of common carotid artery. To observe the aggregation of platelet by using the PRP of the rabbit and ADP as the accelerant. PAG-1, PAG-3, PAG-5 and PAG-M were examined in the normal saline group and high-dose, middle-dose, low-dose groups of Fuxin tablet. Results High-dose and middle-dose groups of Fuxin tablet could prolong OT and decrease the aggregation of platelet. Conclusion Fuxin tablet could significantly inhibit the formation of thrombus in the arteries and maximal aggregation rate of platelet.