The Association between Urine Albumin to Creatinine Ratio and Osteoporosis in Postmenopausal Women with Type 2 Diabetes
Journal of Bone Metabolism
; : 1-7, 2016.
Article
en En
| WPRIM
| ID: wpr-57552
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass density and destruction of microstructure, which can lead to an increased risk of fracture. Although many studies have been published about the relationship between end-stage renal disease and osteoporosis, research on the relationship between proteinuria and the prevalence of osteoporosis is still lacking. METHODS: We assessed 91 postmenopausal women with type 2 diabetes who visited our hospital from January 2009 to January 2012. RESULTS: Among 91 patients, the prevalence of osteoporosis and osteopenia was 35.2% (32 cases) and 32.9% (30 cases) according to bone mineral density. The patients with microalbuminuria and macroalbuminuria (urine albumin-to-creatinine ratio [UACR] > or = 30) had a significantly higher incidence of osteoporosis compared to subjects with normoalbuminuria (P<0.05). CONCLUSIONS: This study indicates that UACR may be a useful biomarker for increased risk of osteoporosis in postmenopausal women with type 2 diabetes who have been linked to higher UACR levels.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Osteoporosis
/
Proteinuria
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Enfermedades Óseas
/
Enfermedades Óseas Metabólicas
/
Densidad Ósea
/
Incidencia
/
Prevalencia
/
Creatinina
/
Albúminas
/
Fallo Renal Crónico
Tipo de estudio:
Incidence_studies
/
Prevalence_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Journal of Bone Metabolism
Año:
2016
Tipo del documento:
Article