THE EXPRESSION OF SUBSTANCE P AND SUBSTANCE P RECEPTOR IN THE DEVELOPMENT OF MOUSE BRAIN / 解剖学报
Acta Anatomica Sinica
; (6)2002.
Article
en Zh
| WPRIM
| ID: wpr-575823
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the expression of substance P(SP) and substance P receptor(SPR) during the development of mice brains. Methods The expression of SP and SPR during the development of mice brains from embryonic day(E) 11 to postnatal day(P) 0 days was analyzed by immunohistochemical method. Results The expression of SP began at E11 and gradually increased until birth. The expression of SPR began at E11 and maintained stable expression until birth. SP mostly expressed at striatum and SPR mostly expressed at medullary raphe.Conclusion The expression of SP and SPR during the embryo brain stage may indicate that SP could be an important factor involved in the early organization and maturation of neuron.
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WPRIM
Idioma:
Zh
Revista:
Acta Anatomica Sinica
Año:
2002
Tipo del documento:
Article