Analgesic and anti-inflammatory activities of brucine nano-liposome for local use on skin / 中成药

ABSTRACT

AIM: To compare brucine with the mixed solution of brucine and nano-liposomes to observe analgesic and anti-inflammatory effects of the brucine nano-liposome for local use on skin were studied. METHODS: The effects of brucine,brucine and nano-liposomes mixed solution,brucine nano-liposome,on the edema of mouse ear induced by dimethylbenzene and the writhing induced by acetic acid were investigated. RESULTS: The results showed that brucine nano-liposomes exhibited better anti-inflammatory and analgesic activities than the brucine.(P