Effect of operative methods on the prognosis of bladder-preserving patients with bladder transitional cell carcinoma / 重庆医科大学学报

ABSTRACT

Objective:To investigate the correlation between overall recurrence rate,survival rate,and the first recurrence duration and operative methods,and to discuss the strategy of bladder-preserving for patients with bladder transitional cell carcinoma(TCC).Methods:A total of 249 cases of bladder tumor with complete follow-up data,treated from 1991 to 2005 in our hospital,were studied re trospectively.The correlation between overall recurrence rate,survival rate and the first recurrence duration and operative methods were analyzed by the life table method,and statistical methods,like Newman-Keuls and chi-square test.Result:The first recurrence duration was not influenced by operative methods. There was no significant difference of overall recurrence rate and short-term survival rate(3-year and 5-year)among different operative methods,the highest 10-year survival rate(77.3%)occurred in the group of transurethral resection of bladder tumor(TURB)and the lowest one(65.2%)in the group of partial cystectomy,and the difference was statistically significant.Conclusions:TURB could achieve the same short-term therapeutic effect as opening operations(partial resection of bladder or resection of bladder tumors)and the higher long-term survival rate can be obtained by TURB.