Mechano-chemical Signal Pathway of Endothelial Cells Migration Induced by Fluid Shear Stress / 航天医学与医学工程
Space Medicine & Medical Engineering
; (6)2006.
Article
en Zh
| WPRIM
| ID: wpr-577049
Biblioteca responsable:
WPRO
ABSTRACT
The migration of endothelial cell induced by fluid shear stress is related to many physiological and pathological responses in organism.The redistribution of membrane receptors and proteins,caused by shear stress,is a vital step for cell migration,followed by chemical reactions and signal transduction.Then cell morphological changes are induced,such as polarity,protrusion,and adhesion,which lead to the migration of endothelial cell at last.The goal of this paper is to review what is known about the mechanical models of endothelial cell migration and the responses of cells to fluid flow.It is helpful for better understanding the intrinsic mechanism of mechano-chemical signal pathway of the migration of endothelial cells induced by fluid shear stress.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Space Medicine & Medical Engineering
Año:
2006
Tipo del documento:
Article