Purification of Dayuan Dropping Pills extract with macroporous resin / 中草药

ABSTRACT

Objective To study the adsorption function of macroporous resin for purifying the extract of Dayuan Dropping Pills and to investigate the purification process of Dayuan Dropping Pills by macro-porous adsorption resin. Methods Taking the content and the extraction rate of baicalin as the main standard index, and the adsorption characters as well as the purification capacities of eight types of macroporous adsorption resins,such as NKA-12, HPD-600, HPD-500, HPD-300, HPD-100, D101, AB-8,and NKA-9, used to treat baicalin of Dayuan Dropping Pills were investigated preliminarily. Results The appropriate adsorption conditions were the concentration of baicalin was 2.65 mg/mL, flow rate was 3 BV/h, the effect of desorption was satisfactory when 50% alcohol (5 BV) and water (4 BV) were used as eluant. Conclusion HPD-300 resin can be applied to refine the Dayuan Droppingp Pills.