Effect of matrine on signaling transduction pathway of JAK-STAT in SMMC-7721 cell line

Fei YIN; Junyan ZHAO; Shukun YAO

Effect of matrine on signaling transduction pathway of JAK-STAT in SMMC-7721 cell line / 中草药

Fei YIN; Junyan ZHAO; Shukun YAO.

Chinese Traditional and Herbal Drugs ; (24)1994.

Artículo en Chino | WPRIM | ID: wpr-578205

ABSTRACT

ABSTRACT

0.05). Conclusion Matrine could significantly down-regulate the mRNA expression of stat3 and stat5 and protein expression of STAT3 and STAT5 in SMMC-7721 cells. So matrine could inhibit the signaling transduction pathway of JAK-STAT and inhibit the proliferation of SMMC-7721 cells.

matrine; JAK-STAT pathway; proliferation; AG490

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Traditional and Herbal Drugs Año: 1994 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Traditional and Herbal Drugs Año: 1994 Tipo del documento: Artículo