Espression and significance of MMP-14 and MMP-2,TIMP-2 in gastric cancer / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2007.
Artículo
en Chino
| WPRIM
| ID: wpr-578417
ABSTRACT
Objective:
To detect the expression of MMP-14,MMP-2 and TIMP-2 in gastric ulcer tissues, gastric cancer and tissues around gastric cancer.Methods:
The expression of MMP-14,MMP-2,and TIMP-2 were detected by S-P immunohistochemistry in gastric ulcer tissues,gastric cancer tissues and around tissues from operated patients of gastric cancer (n=30) and gastric ulcer patients(n=20)who were diagnosed by stomach lens.Results:
(1) The expression rates of TIMP-2, MMP-2 and MMP-14was 43.3%,76.7% and 53.3% respectively in gastric cancer tissues and 56.7%,46.7% and 40%in tissues around it,but 70%,45% and 30% in gastric ulcer tissues. (2) The expression of TIMP-2 in gastric cancer was lower than that in tissues or that in gastric ulcer tissues(P0.05).The expression of TIMP-2 was negatively correlated with the expression of MMP-2 or MMP-14(rs=-1.0,P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Chongqing Medical University
Año:
2007
Tipo del documento:
Artículo
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