Analysis of pathological and clinical manifestations in 377 children with renal disease / 重庆医科大学学报

ABSTRACT

Objective:To explore the relationship between the pathological classification and clinical manifestations of renal glomerular disease in children. Methods:Pathological diagnosis and laboratory routine examinations of total 377 patients with renal disease during Feb,1999 to Feb,2006 were reviewed and compared. Results:(1)There were 250 male and 127 female among 377 patients who received renal biopsy,and the ratio of male to female was 1.97. Among these patients,217(57.6%) cases of primary glomerular disease,158(41.9%) cases of secondary glomerular disease,1(0.25%) case of heritage glomerular diseases and 1 case of renal vascular disease were found, respectively. (2)The most common clinical diagnosis and pathological category in primary glomerulary disease were nephritic syndrome and mesangial proliferative glomerulonephritis(MsPGN), respectively,and that in secondary glomerulary disease were Henoch-Schonlein purpura nephritis and MsPGN,respectively. The mean age in group of secondary glomerulary disease[(10.36?2.83)years] was older than that in group of primary glomerulary disease[(9.72?3.07)years],(P