Effect of Pingshen Tongluo Jiangya Granula on Blood Pressure and RAS of Spontaneously Hypertensive Rat / 中国中医药信息杂志
Chinese Journal of Information on Traditional Chinese Medicine
;
(12)2006.
Artículo
en Chino
| WPRIM
| ID: wpr-578986
ABSTRACT
Objective To investigate the effect of the Pingshen Tongluo Jiangya granula on the blood pressure and RAS of spontaneously hypertensive rat (SHR). Methods SHR were randomly divided into model group, high dosage group, lower dosage group and captopril group, with normal Wistar rats as control group. Different dosage of Pingshen Tongluo Jiangya granula, captopril and water wes given orally to the rats at the same time of a day for 8 weeks. Blood pressure, AngⅠ, AngⅡ and ALD were determined respectively before treatment and 1, 2, 4, 6, 8 week. Results After eight weeks, the blood pressure of high dosage of Pingshen Tongluo Jiangya granula group had stepped down obviously (P 0.05). It shows that the granula could decrease blood pressure, inhibit the activity of RAS caused by high blood pressure. Conclusion The granula can decrease blood pressure smoothly and steadily, as well as reverse early stage of renal damage caused by high blood pressure.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Information on Traditional Chinese Medicine
Año:
2006
Tipo del documento:
Artículo
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