Evaluation of release similarity of multicomponents in Zuojin Sustained-Release Tablet by the total quantum statistical moment similarity / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Artículo
en Chino
| WPRIM
| ID: wpr-579125
ABSTRACT
AIM:
To study and evaluate release rules of Zuojin Sustained-Release Tablet(ZJSRT).METHODS:
The total quantum statistical moment similarity(TQSMS)was used to evaluate similarity of the chromatographic fingerprints of ZJSRT in vitro dissolution;RESULTS:
Compared with the chromatographic fingerprint of the complete dissolution sample,the averages of area under curve of total quantum,mean chromatographic retention time of total quantum and variance of mean chromatographic retention time of total quantum of the ZJSRT's release rules in vitro,from 1 to 12 h,were 2.620?10~8 ?v?sec,74.599 min and 252.481 min~2 respectively,meanwhile their RSD were 62.445%、1.268% and 2.777% coincidently,the similarities range from 0.947 to(0.991,)as average of 0.977 and RSD of 1.491%.CONCLUSION:
It is suggested that the TQSMS can evaluate release rules of multicompon and control its quality.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Traditional Patent Medicine
Año:
1992
Tipo del documento:
Artículo
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