Quality Standard Research of Guishen Pills / 中药新药与临床药理

ABSTRACT

Objective To establish the quality standard of Guishen Pills.Methods The qualitative analysis of Cortex Eucommiae and Fructus Lycii in Guishen Pills was carried out by TLC,and the content of loganin in Guishen Pills was determined by HPLC.Results The chromatographic spots of Cortex Eucommiae and Fructus Lycii were identified without the interference of negative control.A linearity of loganin was obtained from 0.188 ?g to 0.940 ?g with a good correlation(r=0.999 8,n=6).The average recovery was 99.00 % and the RSD was 1.02 %.Conclusion The qualitative and quantitative methods established in this study are simple,feasible,accurate and reproducible,and can be used as the quality control standard for Guishen Pills.