The effect of mild hypothermia on neuronal apoptosis and Bcl-2,Bax in the focal cerebral ischemia in rats / 临床神经病学杂志
Journal of Clinical Neurology
;
(6)1997.
Artículo
en Chino
| WPRIM
| ID: wpr-582356
ABSTRACT
Objective To study the effect of mild hypothermia on neuronal apoptosis and Bcl 2,Bax during cerebral ischemia in middle cerebral artery occlusions(MCAO) in rats.Methods The model of MCAO was set up in rats using the Longa's way,and mild hypothermia was treated for 0.5h,1h,3h. After reperfusion(24h) the rat brains were cut into three sections for TUNEL staining and Bcl 2?Bax protein immunohistochemical staining.Results 1)The numbers of apoptotic cells and Bax cells in the mild hypothermia group(1h, 3h) decreased remarkable as compared with the control group( P
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Clinical Neurology
Año:
1997
Tipo del documento:
Artículo
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