A experimental study on the relationship between transforming growth factor ?_1 and diabetic cardiomyopathy / 中国糖尿病杂志
Chinese Journal of Diabetes
;
(12)1994.
Artículo
en Chino
| WPRIM
| ID: wpr-582377
ABSTRACT
Objective To observe the changes of the levels of transforming growth factor ? 1(TGF ? 1),fibronectin(FN),laminin(LN) and collagen content and myocardium ultrastructure in streptozotocin experimental diabetes mellitus rats.To study the role of TGF ? 1 and extracellar matrix(ECM) in diabetic cardiomyopathy episode.Methods Observing myocardium ultrastructure by electron microscope and assaying TGF ? 1,FN,LN by immunohistochemistric,and observing collagen content by VG staining.Results TGF ? 1,FN,LN were expressed more in STZ inroduced diabetic rats than in normal rats.The difference between two groups was significant ( P
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Diabetes
Año:
1994
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS