Study on the coagulation changes in type 2 diabetes patients / 中华检验医学杂志

ABSTRACT

Objective To investigate the variation of coagulation markers and its clinical value in type 2 diabetes patients. Methods The plasma levels of von Willebrand factor antigen (vWF Ag), thrombomodulin (TM), prothrombin fragment 1+2 (F 1+2 ) and P selectin were measured by ELISA in 65 patients with type 2 diabetes (including 33 patients with vascular complication) and 38 healthy people. Results The plasma level of vWFAg, TM, F 1+2 and P selectin in group of type 2 diabetes were significantly higher than that of normal controls ( P