Stereotactic radiotherapy for lung carcinoma / 中国微创外科杂志

ABSTRACT

Objective To discuss the clinical effects of stereotactic radiotherapy in the management of lung cancer. Methods Included in this study there were 27 patients with lung cancer. After the lesions were localized by CT scans with 2 mm slice thickness, the images were reconstructed and clinical tumor volume (CTV), planning tumor volume (PTV) and dose-volume histograms of the involved lung were calculated. By using Leibinger stereotactic radiotherapy planning system and Varian Clinic 600C, a series of 5～8 fractions of radiotherapy were carried out once daily with 5～7 Gy per fraction. Results None of the 27 patients died during the treatment. General conditions of the patients were assessed by means of Karnofsky performance status (KPS). Preoperative KPS scores were 20～80 (mean 59), while postoperative KPS scores were 20～100 (mean 87). Follow-up information revealed 4 cases of complete remission, 17 cases of patial remission, 2 cases of no change and 4 progressed, with control rate being 85%. Conclusions Stereotactic radiotherapy provides excellent short-term curative effects in the treatment of lung carcinoma.