Two Lung Masses with Different Responses to Pemetrexed
The Korean Journal of Internal Medicine
;
: 213-216, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-58452
ABSTRACT
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lung masses could have originated from different clones or they could have progressed through different paths of molecular pathogenesis after metastasis, which would lead to different tumor characteristics, including their chemosensitivity. Regardless of their pathogenetic mechanisms, it seems important to recognize that tumors with the same histology that develop in one patient can have different responses to drugs.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Carcinoma de Células Escamosas
/
Carboplatino
/
Neoplasias Primarias Secundarias
/
Resistencia a Antineoplásicos
/
Desoxicitidina
/
Glutamatos
/
Guanina
/
Neoplasias Pulmonares
/
Antimetabolitos Antineoplásicos
/
Antineoplásicos
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
The Korean Journal of Internal Medicine
Año:
2010
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS