The structure of epstein-barr virus latent membrane protein 1 and its signal transduction / 医学研究生学报
Journal of Medical Postgraduates
; (12)2003.
Article
en Zh
| WPRIM
| ID: wpr-585241
Biblioteca responsable:
WPRO
ABSTRACT
Epstein-Barr virus is a kind of herpes virus that has oncogenic potential and is related to the tumorgenesis process of various malignancy. Important advances have been obtained on the study of the structure and functions of Epstein-Barr virus(EBV) latent membrane protein 1(LMP1) and signal transduction pathways mediated by LMP1 in recent years. LMP1 could regulate cellular growth, proliferation, transformation, differentiation, transference and apoptosis by means of signal transduction pathways such as NF-?B, AP-1, JAK/STAT, Ets1, MAPK/ATF2 and cyclin dependent kinase.
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WPRIM
Idioma:
Zh
Revista:
Journal of Medical Postgraduates
Año:
2003
Tipo del documento:
Article