Clinical Study of Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) on Drug Eruption Patients Over the last 10 years (1995-2004) / 대한피부과학회지
Korean Journal of Dermatology
;
: 1164-1169, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-58557
ABSTRACT
BACKGROUND:
Drug rash with eosinophilia and systemic symptoms (DRESS), previously named drug `hypersensitivity syndrome', is a subset of severe drug eruption with quite distinct clinical presentations. Perhaps because of its relatively late onset and variable presentations, the diagnosis of DRESS may be delayed.OBJECTIVE:
This study was designed to determine the incidence and investigate the causative drugs and clinical characteristics of DRESS.METHOD:
We retrospectively reviewed the clinical features and laboratory findings of DRESS in 795 drug eruption patients who had visited Pusan National University Hospital over the last 10 years (1995-2004).RESULTS:
1. Of 795 drug eruption patients, 14 (1.76%) received a diagnosis of DRESS. 2. The average age of onset was 44.5 years and there was no significant difference according to sex. 3. The most common causative agent of DRESS was carbamazepine (50%), followed by allopurinol, captopril, phenytoin and antituberculous medications. 4. DRESS developed 2-10 weeks after administration of the causative agent, and the average latent period was 4.6 weeks.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fenitoína
/
Carbamazepina
/
Captopril
/
Alopurinol
/
Incidencia
/
Estudios Retrospectivos
/
Erupciones por Medicamentos
/
Edad de Inicio
/
Diagnóstico
/
Eosinofilia
Tipo de estudio:
Estudio diagnóstico
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2005
Tipo del documento:
Artículo
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