Identification of a novel Bx allele in a Chinese Han individual with B subgroup / 中国输血杂志
Chinese Journal of Blood Transfusion
;
(12)1988.
Artículo
en Chino
| WPRIM
| ID: wpr-585953
ABSTRACT
T missense mutation in exon 7. No novel point mutation at exons 6 and 7 of ABO gene was detected in the other four samples with B subgroup. Conclusion We define this allele as a novel B allele in Chinese Han individuals. The mutation of this novel allele in which the nucleotide changes from C to T at position 721 in exon 7, resulting in an amino acid change from Arg to Trp, results in the decrease of the enzyme activity. It indicates that the alteration of amino acid at position of 241 is critical to the activity of glycosyltransferases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
Idioma:
Chino
Revista:
Chinese Journal of Blood Transfusion
Año:
1988
Tipo del documento:
Artículo
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